Colibacillosis

Colibacillosis
Disease of neonates cause by pathogenic strain of E Coli. 3 type of strain involved
● Enterotoxigenic strain
● Septicemic strain
● Enterohaemorrhagic strain
 Epidemiology
Young ones of all animals, poultry, and human are affected. Most susceptible age is 1st 4 days of life. Usually disease occur within 24 hours
 Transmission
● Fecal- Oral route
● Mucous membrane of nasal passages, oro-pharynx
● Umbilical route
Morbidity 75%
Mortality 50%
Clinical findings
■ In case of enteric form
● Diarrhea pale yellow/white watery
● Dehydration
● Anorexia
● Feaces pass effort less no ( straining)
■ In case of septicemic form
● Fever
● Hypothermia
● Recumbency
● Decrease Blood pressure
● Dry and cool mucous membranes
● Disseminated intravascular coagulation (DIC)
 Diagnosis
On basis of clinical Signs and symptoms
Laboratory tests include
● feaces culture
● PCR
Treatment
Several antibiotics combinations are used
● Amoxicillin 7-10 mg/kg
● Ampicillin 10 mg/kg
● Enrofloxacin 5mg/kg
● Oxytetracycline pvp 11mg/kg and LA 20mg/kg
Supportive treatment
● Ringer lactate
● NSAIDs
● Multivitamins
● Intestinal protectants eg kaolin powder
 Prevention/Control 
● Provide proper amounts of colostrum at proper time to young ones
● Vaccination
● Hygienic conditions
● Stress should be minimized